张晓光，  邹  宏，  曹  龙
    （中国航空规划建设发展有限公司，北京100120）

[摘要] 针对生物制药厂房荷载大、柱网大、层高高的特点，对不同烈度区（7、8度）、不同场地类别（II、III类）的多层框架结构生物制药厂房进行多次计算，得出了生物制药厂房结构在不同楼面活荷载、不同梁板布置时的主要梁柱截面、混凝土用量、钢筋用量。同时也对新、旧抗震规范对此种厂房工程量的影响进行了对比。通过分析，对多层框架结构生物制药厂房进行优化设计，可供确定方案时估算工程量，给以后类似工程提供参考。
[关键词] 生物制药厂房；优化设计；工程量
中图分类号：TU375.4    文献标识码：A  文章编号：1002-848X(2011) S2-0091-03

    Optimized design for bio-pharmaceutical factory building of multi-frame structure
    Zhang Xiaoguang, Zou Hong, Cao Long
    ( China Aviation Planning and Construction Development Co.,  Ltd.,  Beijing 100120,  China)

Abstract: For bio-pharmaceutical factory building characteristics of heavy load, big column grid and high-storey, multiple bio-pharmaceutical factory building model of multi-frame structure were calculated in different seismic precautionary intensity (7,8 degrees) and in different site classification( II, IIIclass). The main beam and column cross-section, the amount of concrete and steel bar of tlus kind bio-pharmaceutical factory building were conducted by different live load and different layout of beam slab. Also the impacts of the old and new code for seismic design of buildings to such plant engineering quantities were compared. Through analysis, optimized design of bio-pharmaceutical factory building was done, and it is valuable to estimate the amount of work for detemuning the scheme. It can also provide reference to future similar projects.
Keywords: bio-pharmaceutical factory building; optimized design; engineering quantity